A legion of biological processes like DNA recombination and replication, gene transcription, DNA repair, chromosomal stability, chromosome segregation, epigenetic silencing, cell cycle progression, and regulation of gene expression are mediated through protein–DNA interactions. Chromatin Immunoprecipitation testing is a method for investigating the DNA-protein interaction. Chromatin Immunoprecipitation also referred as ChIP, is a type of tool that helps in determining the location of the DNA binding sites on the genome for a protein of interest. Chromatin Immunoprecipitation is generally more of a qualitative approach than a quantitative one. Chromatin Immunoprecipitation testing also helps in determination of particular location in the genome that certain histone modifications are linked with, which further indicates targets for histone modifiers. Chromatin Immunoprecipitation is also used for the study of protein modification site or transcriptional factor binding site. With the development of Next Generation Sequencing, the combination of Chromatin Immunoprecipitation and Next Generation Sequencing, Chromatin Immunoprecipitation Sequencing (ChIP-Seq), is now capable of screening and identification of the protein binding sites on the complete chromosomal scale with high and improved accuracy and efficiency.
Chromatin Immunoprecipitation Testing Market: Drivers and Restraints-
Growing incidence of immunology cases require testing for antibody-antigen interaction is one of the major factors boosting the growth of Immunoprecipitation testing market. Increasing funds by the government for researches conducted on combining next generation sequencing and chromatin Immunoprecipitation is also driving the market for chromatin Immunoprecipitation testing. Chromatin Immunoprecipitation testing can also be used for testing occurrence of cardiovascular diseases, cancer and central nervous disorders as well as for mechanisms of embryonic stem cells. This is expected to drive the market for chromatin Immunoprecipitation testing during the forecast period. Although, chromatin Immunoprecipitation testing for human adipose tissue has certain limitations. Limitation factors include, sample size constraintHealths, high lipid content variations, frozen sample availability and cellular composition of the tissues. These factors might hinder the market growth for Immunoprecipitation testing during the forecast period.
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Chromatin Immunoprecipitation Testing Market: Segmentation
On the basis of Product type, Chromatin Immunoprecipitation Testing Market can be segmented as:
- Protein A Magnetic Beads for Chromatin Immunoprecipitation testing
- Protein G Magnetic Beads for Chromatin Immunoprecipitation testing
On the basis of ChIP type, Chromatin Immunoprecipitation Testing Market can be segmented as:
On the basis of Applications, Chromatin Immunoprecipitation Testing Market can be segmented as:
- Cardiovascular Diseases
- Central Nervous Disorders
On the basis of end users, Chromatin Immunoprecipitation Testing Market can be segmented as:
- Research Institutes
- Diagnostic Centers
On the basis of geography, Chromatin Immunoprecipitation Testing Market can be segmented as:
- North- America
- Eastern Europe
- Western Europe
- Asia-Pacific excluding China & Japan
- Middle East and Africa
- Latin America
Chromatin Immunoprecipitation Testing Market: Overview
Global Chromatin Immunoprecipitation Testing market has witnessed growth due to expanding demand for Immunoprecipitation testing for various diseases like cancer and certain cardiovascular conditions. Chromatin Immunoprecipitation Testing is extensively being performed for research purposes. Magnetic protein beads are highly preferred because of the cost effectiveness associated to it. Magnetic beads in chromatin Immunoprecipitation testing allow quicker washes and make use of less antibodies with each Immunoprecipitation. The DNA fragments while the Immunoprecipitation are isolated and can be identified by various methods like, DNA microarray, PCR and DNA sequencing. Combining NGS with ChIP, is also expected to contribute to boost the demand for chromatin Immunoprecipitation testing.
Chromatin Immunoprecipitation Testing Market: Region-wise Outlook
Geography wise, Chromatin Immunoprecipitation Testing market is divided into eight regions viz. North-America, Asia- Pacific excluding China & Japan, China, Japan, Western Europe, Eastern Europe, Latin America and Middle-East & Africa. North America’s Chromatin Immunoprecipitation Testing market is expanding because of high adoption rate and it will remain dominant over the period of forecast due to growing number of research facilities and increased funding by the government for the research studies. Europe’s Chromatin Immunoprecipitation Testing market is also expected to grow at a significant rate due to improved availability of Chromatin Immunoprecipitation Testing kits and growing diagnostic centers in the region. Asia-Pacific’s Chromatin Immunoprecipitation Testing market is anticipated to grow at a decent rate due to low healthcare expenditure.
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Chromatin Immunoprecipitation Testing Market: Key Market Participants
Some of the market participants in the Global Chromatin Immunoprecipitation Testing market identified across the value chain include: Creative Diagnostics, Profacgen, Merck KGaA, Bio-Techne, Abcam plc, Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., BioLegend, Inc., Active Motif, and Thermo Fisher Scientific Inc.